患有乳腺癌的女性患有肉类的风险:对查工具的比较分析
Vanusa Felicio de Souza Mamede1, Rayne de Almeida Marques Bernabé1, Thalita Gonçalves Santos2
1Postgraduate Program in Nutrition and Health, Health Sciences Center, Federal University of Espírito Santo, Vitória, Espírito Santo, Brazil.
BMC cancer
|May 7, 2025
概括
在乳腺癌患者的查中,SARC-CalF显示出对查肉类风险的最佳表现,尽管它的低敏感性建议谨慎. 建议对这一群体的查工具进行进一步评估.
科学领域:
- 在瘤学瘤学.
- 老年病的医生 老年病的医生
- 肌肉骨健康 肌肉骨健康
背景情况:
- 标志着肌肉质量和力量损失的萨科佩尼亚与乳腺癌患者的不良结果有关.
- 目前,没有经过验证的工具专门评估了这一人口群中的肉症风险.
- 这项研究旨在评估SARC-F,SARC-CalF和BMI调整后的SARC-CalF,以查麻症风险查.
研究的目的:
- 为了比较SARC-F,SARC-CalF和BMI调整后的SARC-CalF在识别肉症风险方面的有效性.
- 为了确定乳腺癌妇女的萨尔科佩尼亚最佳查工具.
主要方法:
- 一项观测横截面研究包括168名在前12个月内被诊断患有乳腺癌的妇女.
- 使用EWGSOP2标准定义了肉症:握力低 (<23.0公斤) 和尾骨肌质量指数低 (<6.38公斤/米2).
- 用敏感度,特异性,预测值和AUC来评估查工具的性能,并通过DeLong的测试比较AUC.
主要成果:
- 萨尔科佩尼亚风险的患病率因工具而异 (10.1%36.6%),总体萨尔科佩尼亚患病率为8.3%.
- SARC-CalF显示出最高的AUC (0.790),具有42.8%的灵敏度和92.2%的特异性.
- SARC-F (AUC 0.550) 和BMI调整后的SARC-CalF (AUC 0.521) 的表现较差.
结论:
- 在评估的查工具中,SARC-CalF表现最好.
- 尽管SARC-CalF的性能优越,但其低灵敏度表明需要重新考虑其实用性.
- 需要进一步的研究来完善或确定更有效的查策略,以检测乳腺癌患者的肉症风险.
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