在儿童中穿孔的胃:一个系统的审查
Stipe Vidović1, Sara Borović2, Marko Bašković3,4
1Faculty of Medicine Osijek, Josip Juraj Strossmayer University of Osijek, Osijek, 31 000, Croatia.
BMC pediatrics
|May 7, 2025
概括
儿童的穿孔性胃潰瘍 (PPU) 在男性和十二指腸中更常見. 手术修复,通常用,是有效的,显示低并发症和死亡率.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床研究 临床研究
背景情况:
- 穿孔性胃潰瘍 (PPU) 是胃潰瘍疾病的嚴重并發症,死亡率高.
- 对于儿科人口中PPU,没有先前的系统审查.
- 本综述综合了关于儿童PPU的当前知识.
研究的目的:
- 系统地审查关于儿童穿孔性胃潰瘍的文献.
- 确定儿科PPU的风险因素,常见病因和治疗策略.
- 总结结果,包括并发症和死亡率.
主要方法:
- 在四个主要数据库 (Web of Science,Scopus,PubMed,ScienceDirect) 进行了系统的文献搜索.
- 在研究选择和数据提取方面遵循了PRISMA指南.
- 包括以18岁以下患者的穿孔性胃潰瘍为重点的研究,以英语出版.
主要成果:
- 分析了12项包括239名儿科患者的研究.
- 在男性 (74.8%) 和十二指肠 (73%) 中,PPU的频率更高.
- 手术干预,主要是用进行开放修复,在86.6%的病例中进行,死亡率为3.8%.
结论:
- 儿童的穿孔性胃主要影响男性和十二指肠.
- 使用或不使用指甲贴片进行抽是一种常见且有效的治疗方法.
- 需要进一步的研究,以获得有关儿科PPU管理的更强有力的证据.
相关概念视频
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
67
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
67
Peptic Ulcer Disease I: Introduction
104
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
104
Peptic Ulcer Disease IV: Management
51
Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current...
51
Peptic Ulcer Disease V: Surgical Management and Nursing Care
169
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
169
Peptic Ulcer Disease II: Pathophysiology
159
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
159
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
306
Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI) tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining.
306


