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Updated: May 12, 2025

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发育2.0:一个随机对照试验的肥胖预防干预设计为婴儿在儿科初级保健婴儿的干预
Tiffany M Rybak1,2, Sarah E Francis1, Constance A Mara1,2
1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Contemporary clinical trials communications
|May 8, 2025
概括
这项研究介绍了THRIVE 2.0干预计划,该计划旨在通过促进健康的婴儿生长和调节来预防儿童肥胖. 它的目的是评估干预措施.
科学领域:
- 预防儿童肥胖的方法
- 婴儿发育和调节 婴儿发育和调节
- 育儿干预措施 育儿干预
背景情况:
- 儿童超重和肥胖率是前所未有的,婴儿期被认为是发展高体重轨迹的关键时期.
- 婴儿快速生长对后期肥胖的影响可能受到社会经济因素 (种族/族裔,收入) 和婴儿养/睡觉习惯的影响.
研究的目的:
- 确定在婴儿期教导健康的响应式育儿的可行性,可接受性,满意度和初步有效性,以促进生命生长和调节 (THRIVE 2.0) 干预.
- 为了将THRIVE 2.0干预与婴儿肥胖预防的通常儿科初级保健进行比较.
主要方法:
- 第2b期试点随机对照试验在新生儿诊所招募护理人员-婴儿二合.
- 随机分配到THRIVE 2.0干预或通常的儿科护理 (控制).
- 评估可行性,可接受性,满意度,婴儿成长,养和睡眠在多个时间点,直到12个月大.
主要成果:
- 该研究旨在评估条件体重增加得分的初级结果和二次结果,包括照顾者对婴儿线索的认识,舒缓策略的使用和婴儿睡眠卫生.
- 将对THRIVE 2.0的初步疗效与对照组进行评估.
结论:
- 本文概述了THRIVE 2.0 2b期随机对照试验的协议.
- 假设THRIVE 2.0干预措施在预防早期肥胖和促进婴儿健康发育方面表现出有效性.
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