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在INDEPSO-ISPSM关于腹膜恶性瘤的共识 - 方法论.

Swapnil Patel1, Vivek Sukumar2, Somashekhar S P3

  • 1Department of Surgical Oncology, Upkar Hospital and Cancer Institute, Varanasi, India.

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这项研究建立了关于腹膜恶性瘤的细胞还原性手术 (CRS) 和高温腹膜内化学疗法 (HIPEC) 的共识,解决了国际指导方针中的差距. 这些发现为印度和类似地区的外科医生提供了宝贵的临床资源.

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细胞还原性手术是指细胞还原性手术.德尔菲技术 德尔菲技术是什么?腹膜间皮质瘤 (Peritoneal mesothelioma) 是一种发生在腹膜间皮质瘤的疾病.

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科学领域:

  • 手术瘤学手术瘤学
  • 腹腔周围的恶性瘤
  • 基于证据的医学 基于证据的医学

背景情况:

  • 细胞还原性手术 (CRS) 和高温腹腔内化疗 (HIPEC) 的国际指南在临床相关和区域问题上存在局限性.
  • 需要就CRS和HIPEC的特定方面达成共识,特别是在资源有限的环境和特定患者群体.

研究的目的:

  • 为了发展关于细胞还原性手术 (CRS) 和内恶性瘤的高热性内化疗 (HIPEC) 的共识.
  • 解决CRS和HIPEC协议中的证据缺口和区域考虑.

主要方法:

  • 一种经过修改的Delphi技术,涉及两轮在线投票.
  • 一个由29名专家组成的工作组选择了8个关键主题.
  • 一个由56名经验丰富的瘤学家组成的小组通过SurveyMonkey对260个封闭式问题进行了投票.

主要成果:

  • 在两轮会议后,在80.7%的问题上达成共识,参与率高 (98.2%在第一轮,94.6%在第二轮).
  • 在手术后增强恢复 (ERAS) 部分 (93.3%) 的共识最高,在卵巢癌 (68.0%) 的共识最低.
  • 在22.6%的问题上达成了强烈的共识,技术部分的强烈共识率最高 (34.2%).

结论:

  • 形成的共识为外科医生管理腹膜恶性瘤提供了宝贵的临床资源.
  • 这种共识对印度和其他具有类似人口和社会经济背景的地区尤为重要.
  • 该方法和高参与率确保了研究结果的可靠性,以指导临床实践.