在患有多种并发病的患者内静脉铁补充后的伪黑色素双:一个病例报告
Olanrewaju Adeniran1, Ayowumi Andrew Adekolu1, Joshua Kirkpatrick1
1Division of Internal Medicine, West Virginia University, Morgantown, WV, USA.
Case reports in gastroenterology
|May 8, 2025
概括
伪黑色素质双胞胎病 (PD) 是一种罕见的十二指甲状腺疾病. 这种情况表明,静脉注射铁,可能与含硫药物一起,即使没有口服铁摄入,也可能导致PD.
科学领域:
- 胃肠病学 胃肠病学
- 病理学 病理学 病理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 伪黑色肌痛 (Pseudomelanosis duodeni,简称PD) 是一种罕见的病症,会导致十二指肠上有色素斑点.
- 它与慢性病,糖尿病和口服铁等药物有关.
- 静脉注射 (IV) 铁很少与PD相关.
研究的目的:
- 报告可能与静脉注射铁和抗高血压药物相关的PD病例.
- 探索IV铁和药物在PD发展中的相互作用.
主要方法:
- 视觉检查的食道胃管腺镜 (EGD) 用于视觉检查.
- 用珀尔普鲁士蓝色和Fontana-Masson染色进行活检以进行色素分析.
- 审查患者的病史,包括药物使用和以前的EGD发现.
主要成果:
- 一名69岁的女性患有第四期CKD和高血压,呈现PD.
- 活检证实了PD,显示了巨细胞内的铁色素.
- 该患者在6个月前已经接受了IV铁;之前的EGD对PD是负的.
结论:
- 这一案例表明了IV铁补充在PD发展中的潜在作用.
- 含有IV铁和硫的药物之间的相互作用可能会导致PD.
- 活检对于诊断和排除其他疾病至关重要.
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