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中国专家一致认为,在并发化疗放射治疗期间使用基化复合人体颗粒细胞殖民地刺激因子 (2023年版)

Jun Wang¹, Baosheng Li²

¹Department of Radiation Oncology The Fourth Hospital of Hebei Medical University Cancer Institute.

Precision radiation oncology

|May 8, 2025

概括

作为同步化疗放射治疗 (CCRT) 的常见副作用,中性症可以通过基化重组人体粒细胞殖民地刺激因子 (PEG-rhG-CSF) 有效管理. 这份专家共识为其在CCRT期间安全和合理的临床应用提供了指导方针.

科学领域:

在瘤学瘤学.
血液学血液学血液学
药理学药理学是指药理学的学科.

背景情况:

中性是同时进行化学放射治疗 (CCRT) 的常见血液毒性.
这种情况可能导致治疗延迟,剂量减少,发烧性中性质衰竭和严重感染,影响患者的预后和安全.
对于接受CCRT的癌症患者来说,有效的预防和治疗中性衰竭至关重要.

研究的目的:

评估结复合人粒细胞殖民地刺激因子 (PEG-rhG-CSF) 在接受CCRT的患者的安全性和有效性.
通过使用PEG-rhG-CSF建立一个明确的临床途径和用于预防和治疗中性质衰竭的施用途径.
通过专家共识,通过CCRT期间促进PEG-rhG-CSF的合理临床应用.

主要方法:

对PEG-rhG-CSF相关临床指导方针和最新临床数据的审查.
在CCRT的背景下对PEG-rhG-CSF的安全性和有效性数据的评估.
开发基于共识的临床途径和管理建议.

主要成果:

在临床环境中,PEG-rhG-CSF在预防和治疗中性质衰竭方面表现出有效性.
在CCRT期间为PEG-rhG-CSF的临床途径和施用途径制定了明确的指导方针.
专家的共识旨在标准化和优化PEG-rhG-CSF的使用.

结论:

PEG-rhG-CSF是一种有价值的工具,用于管理接受CCRT的患者中性质衰竭.
专家的共识为合理和有效使用PEG-rhG-CSF提供了一个框架.
优化PEG-rhG-CSF应用可以改善CCRT中的治疗坚持和患者的结果.

关键词:

临床共识临床共识同时进行化学或放射治疗.中性热性衰竭中性热性衰竭基化复合人体粒细胞殖民地刺激因子.

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