现场盐探测器 (OSID) 套件:用于监测盐化的替代工具
Mohd Azerulazree Jamilan1, Nurul Aznyda Norizan1, Ahmad Ali Zainuddin2
1Nutrition, Metabolism and Cardiovascular Research Centre, Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, No. 1, Jalan Setia Murni U13/52, Setia Alam, 40170 Shah Alam, Selangor D.E., Malaysia.
MethodsX
|May 8, 2025
概括
现场盐探测器 (OSID) 套件提供了一种可靠,具有成本效益的方法来监测盐水平. 这种经过验证的工具简化了分析,通过精确的盐化检查,确保有效预防缺乏症.
科学领域:
- 公共卫生 营养 公共卫生 营养
- 分析化学 分析化学
- 食品安全 食品安全
背景情况:
- 缺乏仍然是一个全球公共卫生问题,需要有效的盐强化计划.
- 目前的盐含量监测方法往往是劳动密集型和耗时的.
- 准确且易于使用的工具对于确保盐的质量和有效性至关重要.
研究的目的:
- 验证现场盐探测器 (OSID) 套件,以进行可靠的盐分析.
- 评估OSID套件的性能特征,包括线性,检测极限和精度.
- 将OSID套件的结果与盐监测的标准分析方法 (UHPLC) 进行比较.
主要方法:
- 优化了OSID套件的盐量 (346.1 ± 4.9 mg) 和溶液D体积 (39.1 ± 1.2 μL),允许每套100次分析.
- 验证的线性 (R2 = 0.9956),检测极限 (LOD = 3.6 mg/Kg),方法恢复 (89.5%-99.4%) 和不精确性 (CV < 10%) 对于OSID套件.
- 在OSID套件和UHPLC之间使用Blant-Altman图表对60个盐样进行了比较分析.
主要成果:
- 该OSID套件显示出优异的线性和低的LOD,适合盐分析.
- 测试内部,测试间和操作者间的不精确度都低于10%,证实了高精度.
- 十天的质量控制监测显示出在可接受范围内的一致结果.
- 布兰特-阿尔特曼分析显示,OSID套件与UHPLC参考方法之间存在强烈一致.
结论:
- OSID套件是一种经过验证,可靠和精确的工具,用于现场盐分析.
- 它的性能特点和与UHPLC的强大协议使其成为盐监测的经济有效替代品.
- 该OSID套件可以显著帮助确保盐化方案的有效性,以预防缺障碍.
相关概念视频
01:18Effects of EDTA on End-Point Detection Methods
221
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
221
01:17Precipitation and Co-precipitation
1.6K
Precipitation and coprecipitation methods can be used to separate a mixture of ions in a solution. In qualitative inorganic analysis, ions that form sparingly soluble precipitates with the same reagent are separated based on the differences in solubility products. For example, consider the separation of Cu(II) and Fe(II) ions by precipitation as insoluble sulfides. First, copper(II) sulfide is precipitated by the addition of acidic H2S, where the dissociation of H2S is suppressed. Adding H2S...
1.6K