在儿童静脉血栓栓塞之后,体重指数的变化:一个前性队列研究
Mary P Dang1,2,3,4, Maria Hanna5,6, Zhuo Tina Yang1,2
1University of Texas Southwestern Medical Center, Dallas, Texas, USA.
概括
儿科静脉血栓塞栓症 (VTE) 与随着时间的推移增加的体重指数 (BMI) 有关,除了重症监护室 (ICU) 患者. 基于体重的咨询可能有助于在VTE后的恢复.
科学领域:
- 儿科血液学 儿科血液学
- 心血管研究研究心血管研究
- 肥胖研究 肥胖研究
背景情况:
- 儿科急性静脉血栓塞栓症 (VTE) 可能与身体质量指数 (BMI) 随着时间的推移的变化有关.
- 了解这些变化对于确定潜在的临床干预至关重要.
- 以前的研究还没有完全阐明儿童VTE后的BMI轨迹.
研究的目的:
- 为了研究从静脉瘤诊断到诊断后3个月和6个月BMI的变化.
- 在儿科VTE患者中确定BMI变化的预测因素.
- 计算这个群体中超重和肥胖的流行率.
主要方法:
- 在6个月内对63名儿科VTE患者进行前性队列研究.
- 用BMI95 (%BMI95) 的百分比来标准化不同年龄和性别的体重.
- 作为主要结局,分析了BMI%<<95> (Δ%BMI<<95>) 的变化,将重症监护室 (ICU) 与非ICU子组进行比较.
主要成果:
- 62%的参与者在诊断时超重/肥胖.
- 平均BMI95的百分比为102.5%,为95%以下.
- 在3个月和6个月 (分别增加1.5%和2.2%) 观察到的体重增加 (Δ%的BMI<<95>>>0) 特别是在非ICU患者中. 较长的住院预测体重增加,而在ICU中较高的初始BMI%95预测BMI下降.
结论:
- 儿科静脉动脉突发症后的BMI通常会增加,但ICU的患者例外.
- 基于体重的咨询和生活方式的修改是后VTE管理的潜在干预措施.
- 进一步的研究可以探索有针对性的干预措施,以减轻体重增加.
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