松素辅助疗法可能会提高患有酒精使用障碍的患者的保存值
Noah D Gold1,2, Broc A Pagni1, Petros D Petridis1
1Department of Psychiatry, NYU Langone Center for Psychedelic Medicine, NYU Grossman School of Medicine, New York, New York, USA.
Psychedelic medicine (New Rochelle, N.Y.)
|May 8, 2025
概括
松素辅助治疗可能会增加酒精使用障碍患者的保存值. 然而,这些价值变化并没有影响研究中的饮酒结果.
科学领域:
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
- 神经科学是一个神经科学.
背景情况:
- 西辅助疗法 (PAT) 正在针对精神疾病进行研究.
- PAT对酒精使用障碍 (AUD) 患者个人价值的影响尚不清楚.
- 这项研究探讨了PAT对个人价值观和AUD饮酒结果的影响.
研究的目的:
- 为了研究psilocybin辅助治疗对患有酒精使用障碍的患者个人价值观的影响.
- 评估个人价值观的变化,急性迷幻体验和饮酒结果之间的关系.
主要方法:
- 一项II期临床试验涉及93名AUD参与者,接受心理治疗和psilocybin或安慰剂.
- 使用施瓦茨价值调查 (SVS) 测量治疗前和后的个人价值.
- 用神秘体验问卷 (MEQ) 和五维意识改变状态量表 (5D-ASC) 评估了急性迷幻体验.
主要成果:
- 松素辅助疗法显著增加了保护价值领域,特别是"安全"和"传统".
- 在其他价值领域或安慰剂组中没有观察到显著变化.
- 在迷幻体验期间的不可形容性和对自我溶解的恐惧与保护价值的增加相关.
结论:
- 松素辅助疗法可能通过增强保存值来改变AUD患者的价值结构.
- 虽然急性迷幻效应与这些价值变化有关,但它们不能预测饮酒结果.
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