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在接受体外膜氧化治疗的创伤患者中的鼻腔感染
Larisa Shagabayeva1, Luciana Tito Bustillos1, Jessica M Delamater1
1Divisions of Trauma, Burns, and Surgical Critical Care, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, and Jackson Memorial Hospital/Ryder Trauma Center, Miami, Florida, USA.
在外体膜氧化 (ECMO) 治疗中,近一半的创伤患者患上医院感染,主要是呼吸道感染. 格拉姆阴性病原体很常见,具有显著的多药性耐药性,影响死亡率.
科学领域:
- 关键护理医学 关键护理医学
- 传染性疾病 传染性疾病
- 创伤外科 手术 创伤外科
背景情况:
- 需要体外膜氧化 (ECMO) 的急性创伤患者感染的风险尚未确定.
- 这种重症患者群体可能面临患病室感染的风险增加.
研究的目的:
- 在接受ECMO的创伤患者中表征血液和呼吸道病原体.
- 为了测试这些患者对医院感染的独特风险的假设.
主要方法:
- 在一级创伤中心对50名需要ECMO的创伤患者 (不包括烧伤) 的回顾性评估.
- 对血液和呼吸道样本进行病原体鉴定分析.
- 与非ECMO创伤患者感染率的比较.
主要成果:
- 44%的患者患有血流和/或呼吸道感染,主要是呼吸道感染 (70.2%).
- 格拉姆阴性病原体是最常见的;20%的血液流和41.7%的呼吸道分离物是多药耐药的.
- 与没有感染患者 (60%) 相比,感染患者 (22.7%) 的住院死亡率显著更高.
结论:
- 在ECMO治疗的创伤患者中,鼻腔感染率与非ECMO治疗患者相比较.
- 需要进一步的研究来评估感染风险,并为这个患者群开发缓解策略.
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