揭开卵巢膜:对一个难以捉摸的解剖结构的组织学识别
Jeffrey D Seidman1, Rebecca Stone2, Vasiliki A Moragianni3
1Pathology Consultant, Gaithersburg.
The American journal of surgical pathology
|May 8, 2025
概括
卵巢膜,输卵管的一部分,显示了对卵巢和宽带的复杂附着. 了解它的微解剖学对于妇科瘤学和生殖健康至关重要.
科学领域:
- 妇科病理学 妇科病理学
- 生殖解剖学 生殖解剖学
- 手术病理学手术病理学
背景情况:
- 卵巢膜是输卵管的膜末端的一部分,它附着在卵巢上.
- 它的微解剖学和组织学特征尚未完全理解,尽管它具有潜在的临床意义.
研究的目的:
- 为了描述fimbrio-ovarian附件的微解剖学和组织学.
- 研究这些发现对妇科病理学的影响,特别是高度血清癌 (HGSC) 的发展和传播.
主要方法:
- 组织学检查74个附着于卵巢或宽带的手指骨折,没有粘附.
- 表皮和树皮连续性,状形态和相关组织学特征的表征.
主要成果:
- 卵巢膜附着物在51个病例中显示出输卵管和卵巢/腹膜上皮质之间的连续性,在42个病例中显示出 stromal 连续性.
- 异常的状形态 (例如,形,加厚,延长,融合, edematous,纤维化) 是常见的.
- 经常观察到介质细胞组成部分和输卵管-腹膜结;还注意到沃尔萨德细胞巢和初始腺纤维瘤.
结论:
- 卵巢膜表现出复杂的解剖学和组织学特征,这可能对卵巢表面上皮质包容,内分泌症和不孕症的发病产生潜在影响.
- 了解这些特征对于预防性沙切除术至关重要,因为残留部分可以作为HGSC的巢穴.
- 卵巢膜作为子宫外HGSC的潜在原点的作用需要进一步调查.
相关概念视频
Ovaries
534
The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of...
On the ovarian surface, a layer of...
534
Ovarian Cycle
729
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
729
Folliculogenesis
400
Folliculogenesis is the development of ovarian follicles, the specialized structures within the ovarian cortex where oogenesis, or egg development, occurs. This process is essential for female reproductive health and begins during fetal development when primordial follicles are formed. Each primordial follicle comprises a primary oocyte in the center, surrounded by a single layer of squamous pre-granulosa cells. These follicles remain dormant in late prophase I of meiosis until triggered by...
400
Uterine Tubes
370
The uterine or fallopian tubes function as the conduit through which oocytes travel from the ovaries to the uterus. Each fallopian tube measures approximately 10 to 13 cm long and is anatomically divided into the infundibulum, ampulla, isthmus, and interstitial part (or intramural segment). The infundibulum is characterized by its funnel shape and features extensions called fimbriae which reach towards the peritoneal cavity. These fimbriae play a critical role during ovulation as they extend...
370
Oogenesis
711
Oogenesis, the process of developing egg cells (female gametes), occurs within the ovaries and is fundamental to female fertility. This sequence begins during fetal development when diploid oogonia in the developing ovaries undergo mitotic divisions to produce primary oocytes. By birth, these primary oocytes enter prophase I of meiosis but become arrested in this stage, remaining suspended until puberty.
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
Each primary oocyte is surrounded by a layer of pre-granulosa cells, forming what is...
711
Histology of the Uterus
679
The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...
The endometrium is the...
679


