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Updated: May 12, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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通过调节miR-146a-5p/SMAD4轴,METTL3促进口腔状细胞癌

Jayasree Peroth Jayaprakash1, Pragati Karemore1, Piyush Khandelia1

  • 1Laboratory of Molecular Medicine, Department of Biological Sciences, Birla Institute of Technology and Science, Pilani - Hyderabad Campus, Hyderabad 500078, India.

Oncotarget
|May 8, 2025
PubMed
概括

N6-甲基氨酸 (m6A) 修饰调节了口腔癌中的基因表达. METTL3酶控制miR-146a-5p,影响瘤抑制剂SMAD4,揭示了口腔状细胞癌 (OSCC) 的新治疗标.

关键词:
在METTL3中,METTL3是METTL3的第一个类型.在SMAD4中,我们可以看到SMAD4.m6ARNA甲基化的过程在 miR-146a-5p 中使用.口腔癌是口腔癌的一种疾病.

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