偏好lisdexamfetamine与过度饮食障碍的认知行为疗法:相关性和结果
Sydney Yurkow1, Valentina Ivezaj1, Brian Pittman1
1Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.
The Journal of clinical psychiatry
|May 8, 2025
概括
在最近的一项临床试验中,患者对认知行为疗法 (CBT) 或利斯美胺 (LDX) 的偏好没有影响过度饮食障碍 (BED) 治疗结果. 这两种治疗方法都被证明是有效的,无论患者的选择如何.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 过度饮食障碍 (BED) 有有效的治疗方法,但患者的偏好及其对结果的影响仍未得到充分研究.
- 调查患者对认知行为疗法 (CBT) 和利斯美胺 (LDX) 的偏好对于个性化BED治疗至关重要.
- 了解治疗偏好的相关性可以为临床实践提供信息并改善患者参与度.
研究的目的:
- 确定患者对CBT与LDX在BED治疗中的偏好频率和特征.
- 检查患者对CBT或LDX的偏好是否预测或缓解治疗结果.
- 分析患者偏好与BED患者的社会人口统计学/临床因素之间的关联.
主要方法:
- 一个随机对照试验,涉及102名参与者,DSM-5定义BED.
- 参与者在开始治疗之前表示他们更喜欢CBT或LDX;治疗分配是随机的.
- 包括暴饮暴食缓解,体重减轻和精神病理学在内的结果由盲目评估者评估.
主要成果:
- 很大一部分参与者更喜欢LDX (43.1%) 或没有偏好 (33.3%),而更少的人更喜欢CBT (23.5%).
- 治疗偏好与社会人口统计学或基线临床特征无关.
- 没有发现任何显著的相互作用效应,表明偏好并没有适度CBT或LDX的治疗结果.
结论:
- 患者对CBT或LDX的偏好不会影响BED和肥胖患者的治疗结果.
- 无论是CBT还是LDX都是BED的有效干预措施,无论患者的偏好如何.
- 研究结果表明,在临床实践中,重点是治疗疗效,而不是对这些干预措施的偏好.
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