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酸亲密性分子印记共价有机框架,用于高度选择性地识别和提取zearalenone

Jian Song¹, Hai-Long Qian¹, Shu-Ting Xu¹

¹State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, China; International Joint Laboratory on Food Safety, Jiangnan University, Wuxi 214122, China; Institute of Analytical Food Safety, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China.

|May 8, 2025

概括

一种新的亲和分子印记共价有机框架 (BA-MICOF) 从食物中选择性地提取zearalenone (ZEN). 这种方法提供了灵敏而精确的真菌毒素测定,以改善食品安全风险评估.

科学领域:

分析化学分析化学
材料科学材料科学材料科学
食品科学食品科学食品科学

背景情况:

泽拉伦 (ZEN) 是一种经常在食品中发现的有毒真菌毒素.
准确检测ZEN对于食品安全和风险管理至关重要.
现有的ZEN检测方法可能缺乏选择性和灵敏性.

研究的目的:

开发一种新的亲和分子印记共价有机框架 (BA-MICOF) 用于选择性提取.
建立一种敏感和精确的方法,用于在食品矩阵中确定ZEN.
加强食品工业中的菌毒素控制策略.

主要方法:

使用波瓦罗夫反应的一合成酸合并的COF (BA-COF).
通过亲和印记策略制备BA-MICOF.
开发基于BA-MICOF的固体相提取技术,并使用高性能液态染色学 (HPLC) 进行ZEN分析.

主要成果:

合成的BA-MICOF对ZEN具有优越的选择性,其印记因子为10.8.
开发的方法实现了ZEN的0.26μg kg-1的低检测极限.
在ZEN测定中获得了高回收率 (89.3%106%) 和良好的精度 (RSD 1.8%5.4%).

结论:

亲和印记和共价有机框架的组合为选择性污染物捕获提供了有效的方法.
在复杂的食品基质中,BA-MICOF显示了选择性提取和敏感确定ZEN的巨大潜力.
这一进步有助于改善菌根毒素监测和食品安全保证.

关键词:

食品安全食品安全有分子印记的聚合物.菌毒毒素是一种毒素.样品预处理样品预处理固体相提取方法固体相提取方法

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