头癌临床试验中的成本评估:对高价值护理的影响
Rachel G Collins1, Ina A Lee1, Daniel R S Habib1
1Vanderbilt University School of Medicine, Nashville, TN, United States of America.
American journal of otolaryngology
|May 8, 2025
概括
很少有头癌临床试验包括成本结果或成本效益分析. 这限制了对新型癌症治疗对医疗保健系统真正影响的理解.
科学领域:
- 在瘤学瘤学.
- 卫生经济学 卫生经济学
- 临床试验设计 临床试验设计
背景情况:
- 临床试验对于推进头癌疗法至关重要.
- 随着医疗保健成本的上升,需要在试验设计中考虑经济因素.
- 目前在头癌临床试验中的成本考虑特别有限.
研究的目的:
- 评估在多大程度上将成本纳入头癌临床试验.
- 确定这些试验中成本结果和成本效益分析的普遍性.
主要方法:
- 我们对ClinicalTrials.gov进行了全面的搜索,以寻找头癌症研究.
- 研究被确定是否包括成本在描述中或作为结果.
- 提取的数据包括研究类型,持续时间,招生,资金和与成本相关的指标.
主要成果:
- 在2290项头癌试验中,只有3.3%的人提到成本.
- 在提到成本的试验中,成本结果存在于70%的试验中,而成本效益在34%.
- 成本很少是主要结果 (0.2%),大多数结果 (96%) 未报告.
结论:
- 头癌临床试验仅限于成本终点和成本效益分析 (分别为<3%和<2%).
- 报告成本数据的稀缺性阻碍了利益相关者对治疗价值的全面评估.
- 鉴于医疗保健成本压力,在临床试验中增加对成本分析的关注和投资至关重要.
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