循环炎症蛋白和动脉样硬化之间的因果关系:双向的门德尔随机化研究和元分析

Bin Xu1, Qiyang Xu1, Yi Wang2

  • 1Department of Vascular Surgery, Ningbo No.2 Hospital, Ningbo, Zhejiang Province, China.

PubMed
概括

这项研究使用了门德尔的随机化来将循环炎症蛋白 (CIPs) 与动脉样硬化 (AS) 联系起来. 特定的蛋白质如阿尔特明和TNF会增加AS风险,而其他蛋白质如IL-8和IL-6则表现出保护作用,表明新的治疗点.

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