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Updated: May 12, 2025

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新加坡虹膜病毒VP018通过准STING-TBK1-IRF3轴来取消干扰素反应

Wenji Wang1, Linyong Zhi1, Shanxing Liu1

  • 1College of Marine Sciences, South China Agricultural University, Guangzhou 510642, China; Nansha-South China Agricultural University Fishery Research Institute, Guangzhou 511464, China.

International journal of biological macromolecules
|May 8, 2025
PubMed
概括

新加坡群虹膜病毒 (SGIV) 蛋白VP018有助于病毒聚集并逃避宿主免疫力. 它向STING-TBK1-IRF3通路,降解关键蛋白质并阻止对抗病毒防御至关重要的干扰素反应.

关键词:
在 IRF3 中,IRF3 是 IRF3 的一个类型.干扰素 干扰素 干扰素美国国务院GVIV在TBK1中,在VP018中,它是VP018的.病毒组装组件 病毒组装组件

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