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Updated: Jun 15, 2025

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哺乳动物氨酸tRNA修改影响翻译以增强细胞增殖和MHC-II表达

Olivia N P Zbihley1, Katherine Johnson2, Luke R Frietze1

  • 1Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.

Journal of molecular biology
|May 8, 2025
PubMed
概括

在转移RNA (tRNA) 中高水平的queuosine (Q) 修饰增强了人类和小鼠细胞的细胞增殖. 这种tRNA修饰影响基因表达和免疫反应,为各种生物功能提供了洞察力.

关键词:
在MHC-II中,MHC-II是最常见的.基因组RNA的修改 基因组RNA的改变皇后是一个皇后.队列中没有任何东西.这是一个tRNARNA.

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