关于脂蛋白的布鲁塞尔国际宣言 (a) 检测和管理
Florian Kronenberg1, Nicola Bedlington2, Zanfina Ademi3
1Institute of Genetic Epidemiology, Medical University of Innsbruck, Innsbruck, Austria; Lp(a) International Task Force, FH Europe Foundation, Amsterdam, Netherlands.
Atherosclerosis
|May 8, 2025
概括
高脂蛋白 (Lp) 是一个主要的心血管风险,但测试很少见. 布鲁塞尔宣言敦促将Lp (a) 测试纳入早期检测和管理的健康计划.
科学领域:
- 心血管医学 心血管医学
- 公共卫生政策 公共卫生政策
- 遗传风险因素 遗传风险因素
背景情况:
- 升高的脂蛋白 (Lp) 是心血管疾病的显著,独立和因果风险因素.
- 目前的Lp (a) 检测率非常低 (1-2%),尽管20%的人口的检测水平较高.
- 这种差异凸显了心血管风险评估和预防策略的差距.
研究的目的:
- 为了解决全球低脂蛋白水平的测试和管理问题.
- 倡导政策变化和提高对Lp (a) 作为心血管风险因素的认识.
- 促进协调的国际努力,对Lp (a) 进行测试和管理.
主要方法:
- 在比利时布鲁塞尔召开Lp (a) 全球峰会 (2025年3月24日至25日).
- 联合创建布鲁塞尔关于LP国际宣言 (a) 测试和管理由LP国际特别工作组和全球领导人.
- 与科学组织,患者倡导团体和政策制定者合作.
主要成果:
- 布鲁塞尔宣言概述了五个关键的行动呼吁,以改善Lp (a) 测试和管理.
- 这些措施包括将Lp(a) 整合到心血管健康计划中,投资于有针对性的计划,强制进行系统测试,将结果纳入风险评估,并加强教育.
- 该声明强调了主动Lp (a) 管理的成本节约潜力.
结论:
- 系统,报销和终身脂蛋白测试对于预防心血管疾病至关重要.
- 政策整合,投资和教育对于有效的LP (a) 管理至关重要.
- 解决升高的Lp(a) 水平可以显著降低心血管风险和医疗保健成本.
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