遵守韩国国家抗癌法典和死亡率:来自健康检查者-宝石研究的前性队列研究
Jeeyoo Lee1, Aesun Shin1,2,3,4,5, Woo-Kyoung Shin6
1Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.
Epidemiology and health
|May 9, 2025
概括
坚持"韩国全国抗癌法典"的指导方针,可显著降低所有死因,癌症和心血管疾病 (CVD) 的死亡风险. 这种健康生活方式的推广显示了朝鲜成年人减少死亡率的明显好处.
科学领域:
- 公共卫生 公共卫生
- 预防医学 预防医学
- 流行病学 流行病学
背景情况:
- 韩国国家抗癌法典成立于2006年,为癌症预防提供了10条建议.
- 促进健康的生活方式对于降低癌症风险和改善整体健康结果至关重要.
- 了解遵守这些指南对死亡率的影响对于公共卫生战略至关重要.
研究的目的:
- 调查遵守"韩国国家抗癌法典"与死亡风险之间的关联.
- 检查与全因,癌症特异性和心血管疾病 (CVD) 死亡率的关系.
- 为国家癌症预防指南的有效性提供证据.
主要方法:
- 一项前性队列研究,涉及109,160名韩国成年人 (40-69岁) 来自健康检查者-宝石研究 (HEXA-G).
- 坚持得分是基于6个关键的生活方式因素计算的:吸烟,饮食 (水果,蔬菜,盐),酒精,体力活动和体重.
- 考克斯比例危险回归用于估计死亡风险的危险比率 (HR) 和95%置信区间 (CI).
主要成果:
- 在平均12.0年的随访期间,死亡人数为3,799人.
- 坚持性得分最高的男性显示,所有原因 (HR=0.67),癌症 (HR=0.63) 和心血管疾病死亡率 (HR=0.56) 的风险显著降低.
- 女性也表现出所有原因 (HR=0.85) 和心血管疾病死亡率 (HR=0.70) 的风险降低,坚持更高.
结论:
- 坚持"韩国国家抗癌法典"与降低死亡率有显著的关联.
- 这些发现支持实施和推广这些健康生活方式指南,以预防疾病.
- 公共卫生倡议应强调这些建议,以降低癌症,心血管疾病和整体死亡率的风险.
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