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Updated: May 12, 2025

Infection of Primary Nasal Epithelial Cells Grown at an Air-Liquid Interface to Characterize Human Coronavirus-Host Interactions
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德克萨米他破坏细胞内pH稳定,延迟冠状病毒传染性支气管炎病毒通过交换机3激活进入细胞

Jun Dai1,2, Yiyi Feng1, Hong Long2

  • 1Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, China.

Journal of virology
|May 9, 2025
PubMed
概括

德克萨米他 (Dex) 通过激活交换器3 (NHE3) 来抑制冠状病毒传染性支气管炎病毒 (IBV) 复制,从而破坏细胞质 pH 恒温. 这种涉及葡萄糖皮质体受体的机制为抗病毒药物开发提供了新的点.

关键词:
Na+/H+交换器 3 的 3 个冠状病毒冠状病毒的新冠病毒.德克萨米他是一种感染性支气管炎病毒感染性支气管炎病毒它们的pH值为pH.

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