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Updated: May 12, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
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Published on: August 25, 2023

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在家族和双边威尔姆斯瘤中,遗传和表观遗传倾向的不同途径

Jenny Wegert1, Silke Appenzeller2, Taryn D Treger3,4,5

  • 1Developmental Biochemistry, Theodor-Boveri-Institute/Biocenter, Julius-Maximilians-University Würzburg, Am Hubland, Würzburg, 97074, Germany.

Genome medicine
|May 9, 2025
PubMed
概括

对威尔姆斯瘤的遗传倾向涉及基因改变或表观遗传缺陷. 这些发现指导了受影响儿童的遗传查和风险评估,支持液体活检以获得更好的治疗.

关键词:
这就是BWS的BWS.癌症的倾向性 癌症的倾向性基因组印记是指基因组的印记.遗传性癌症是一种遗传性癌症.多中心瘤多中心瘤质细胞瘤 (nephroblastoma) 是一种质细胞瘤.儿科癌症 儿科癌症在WT1中,WT1就是WT1.威尔姆斯瘤是一种瘤.

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