美国老年男性的相对脂肪量和认知功能之间的关联:NHANES 2011-2014年
Linlin Liu1, Anshi Wu2, Shengnan Yang1
1Department of Anesthesiology, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.
Lipids in health and disease
|May 9, 2025
概括
较高的相对脂肪质量 (RFM) 与老年男性的认知功能较差有关. 管理RFM可能有助于减轻这一群体的认知衰退.
科学领域:
- 老年学是一门学科.
- 肥胖问题研究研究
- 认知神经科学 认知神经科学
背景情况:
- 相对脂肪质量 (RFM) 是一种用于评估成年人全身脂肪百分比的新指标.
- 在老年人群中,认知能力下降是一个很大的问题,特别是在男性中.
研究的目的:
- 调查美国老年男性的相对脂肪量和认知表现之间的关联.
- 为了确定增加的身体脂肪是否与老年男性认知能力下降相关.
主要方法:
- 利用来自NHANES (2011-2014) 的1,321名美国老年男性 (60岁以上) 的数据.
- 使用CERAD-WL,AFT和DSST测试评估认知功能,将得分平均成一个复合的Z-score.
- 使用腰围和身高计算RFM;通过多变量线性回归和其他统计方法分析关系.
主要成果:
- 在更高的RFM和认知分数 (CERAD-WL,DSST和复合Z-score) 之间发现了显著的负相关性.
- 当RFM超过35.78%时,RFM和认知功能 (Z分数) 之间的负面关联加剧了.
- 亚组分析显示,教育水平,PIR,吸烟和饮酒状况显著改变了RFM-认知功能关系.
结论:
- 较高的相对脂肪质量与老年男性的认知功能下降有关.
- 控制相对脂肪质量可能是一个可行的策略,以保持男性老龄化的认知健康.
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