在神经退行症中TDP-43酸化的分子机制和后果

Elise A Kellett1, Adekunle T Bademosi2, Adam K Walker3,4,5

  • 1Neurodegeneration Pathobiology Laboratory, Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, St Lucia, 4072 QLD, Australia.

PubMed
概括

TDP-43酸化是神经退行性疾病的关键,如ALS和FTD. 本综述阐明了它在疾病进展和神经保护方面的复杂,取决于背景的作用,强调了特定位置的功能.

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