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Updated: May 14, 2025

Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay
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环林B上的酸盐结合口袋控制着CDK基质酸化和线粒时间

Henry Y Ng1, Devon H Whelpley1, Armin N Adly1

  • 1Department of Physiology, University of California San Francisco, San Francisco, CA, USA.

Nature communications
|May 9, 2025
PubMed
概括

一个新的酸盐结合口袋在B型循环素上,类似于Cks1,调节循环素依赖激酶 (CDK) 基质的多位酸化. 这一发现对于了解细胞循环控制和细胞分裂的稳健时间至关重要.

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