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Updated: Jun 29, 2026

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors
09:33

Imaging Approaches to Assessments of Toxicological Oxidative Stress Using Genetically-encoded Fluorogenic Sensors

Published on: February 7, 2018

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有关不良结果途径的综合测试,以识别通过氧化DNA损伤引起基因毒性的化学物质:对4-尼托基诺林-1-氧化物的案例研究

Elizabeth Huliganga1,2, Eunnara Cho2, Carol D Swartz3

  • 1Department of Biology, University of Ottawa, Ottawa, Canada.

Environmental and molecular mutagenesis
|May 9, 2025
PubMed
概括

这项研究表明,在人类细胞中使用4-尼托基诺林-1-氧化物 (4NQO) 的不良结果途径 (AOP) 告知测试策略. 综合方法成功量化化学诱导的DNA损伤,突变和染色体异常随着时间的推移.

关键词:
负面结果的途径.双重测序是指双重的测序.错误纠正了序列的错误.遗传毒理学遗传毒理学在体外毒理学.新方法方法论新方法方法论

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