Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Overview of Cell Signaling01:23

Overview of Cell Signaling

19.8K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
19.8K
Immune Surveillance by NK Cells and Phagocytes01:25

Immune Surveillance by NK Cells and Phagocytes

927
Immune surveillance is an integral part of the innate immune system, involving the continuous monitoring of peripheral tissues to detect and respond to pathogens, infected cells, or cancerous cells. This surveillance is conducted primarily by natural killer (NK) cells and phagocytes, which employ distinct but complementary mechanisms to identify and eliminate threats.
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
927

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Kidney Health in a Changing Climate: Emerging Disease Patterns and Driving Mechanisms.

Kidney360·2026
Same author

<i>In vitro</i> generation of RORγt<sup>+</sup> regulatory T cells reveals enhanced immunosuppressive function and OXPHOS-dependent metabolism.

Frontiers in immunology·2026
Same author

Birth Weight Measurement Gaps and Global Kidney Health.

Kidney360·2026
Same author

Th17 cells require the DNA repair sensor xeroderma pigmentosum complementation Group C to control oxidative DNA damage in a murine model.

Nature communications·2026
Same author

The Impact of Low-Protein Diet on the Molecular and Cellular Development of the Fetal Kidney.

Journal of the American Society of Nephrology : JASN·2026
Same author

Extracellular Vesicles Facilitate the Crosstalk Between High Glucose-Stimulated Mesangial Cells and Healthy Podocytes to Mediate Injury Responses.

International journal of molecular sciences·2026

相关实验视频

Updated: May 12, 2025

Author Spotlight: Generation of Patient-Derived Podocytes from Skin Biopsies
08:52

Author Spotlight: Generation of Patient-Derived Podocytes from Skin Biopsies

Published on: May 26, 2023

1.9K

智能 podocyte:感知和响应一个复杂的微环境.

John F Bertram1,2, Luise A Cullen-McEwen1, Vinicius Andrade-Oliveira3,4

  • 1Department of Anatomy and Developmental Biology, Biomedicine Discovery Institute, Faculty of Medicine, Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia.

Nature reviews. Nephrology
|May 9, 2025
PubMed
概括

细胞感知并响应其脏的微环境,以维持血液过. 这些过程的失调会导致脏疾病.

更多相关视频

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
12:19

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli

Published on: June 27, 2015

10.9K
Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

296

相关实验视频

Last Updated: May 12, 2025

Author Spotlight: Generation of Patient-Derived Podocytes from Skin Biopsies
08:52

Author Spotlight: Generation of Patient-Derived Podocytes from Skin Biopsies

Published on: May 26, 2023

1.9K
Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli
12:19

Single-channel Analysis and Calcium Imaging in the Podocytes of the Freshly Isolated Glomeruli

Published on: June 27, 2015

10.9K
Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
07:15

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway

Published on: August 23, 2024

296

科学领域:

  • 腎臟病學 (nephrology) 是一種醫學專業.
  • 细胞生物学 细胞生物学
  • 生理学 生理学 生理学

背景情况:

  • 细胞是脏膜过屏障中的关键细胞.
  • 它们在一个独特的微环境中运作,受到机械力和分子交换的影响.
  • 足细胞的生存和功能取决于对环境线索的感知和反应.

研究的目的:

  • 阐明受体细胞对其微环境的感知和响应机制.
  • 了解细胞功能如何影响脏整体健康.

主要方法:

  • 这项研究回顾了细胞与细胞外基质和邻近细胞的相互作用.
  • 它检查了环境传感中涉及的各种信号通路.
  • 分析包括有机体在调节 podocyte 反应中的作用.

主要成果:

  • 细胞感知环境因素,如葡萄糖,脂质,氧气,pH值和压力.
  • 响应机制涉及信号通路和器官功能.
  • 这些反应调节细胞新陈代谢,免疫功能和 podocyte 结构.

结论:

  • 足细胞的感知和反应对于保持球体和脏健康至关重要.
  • 这些过程中的不平衡会导致炎症,细胞损失和球细胞疾病.