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腹腔内利多卡因用于成年人持续的术后止痛的药理动力学

Kenyon W Osborne1, Wiremu S MacFater2, Brian J Anderson3

  • 1Department of Pharmacology and Clinical Pharmacology, University of Auckland, Auckland, New Zealand.

European journal of drug metabolism and pharmacokinetics
|May 9, 2025
PubMed
概括

在腹部手术后,腹腔内皮质利多卡因的吸收缓慢,大约三分之一的剂量没有进入全身循环. 然而,模拟表明,2mg/kg/h输液可以在36分钟内显著降低疼痛评分.

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