跨口腔隔膜切除与Z-POEM在治疗Zenker分泌体:一个多中心的案例匹配比较研究
Luca Provenzano1, Stefano Siboni2, Giovanni Capovilla3
1Department of Surgical, Oncological and Gastroenterological Sciences, School of Medicine, University of Padua, Padua, Italy.
Surgical endoscopy
|May 9, 2025
概括
透口隔膜切除术 (TS) 和透口内镜肌肉切除术 (POEM) 是Zenker分离器 (ZD) 的有效治疗方法. 与Z-POEM相比,TS提供更短的手术时间和更少的手术内并发症.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性的手术
- 消化内镜检查是消化器内镜检查.
背景情况:
- 对于Zenker Diverticulum (ZD) 治疗方法仍有争议.
- 透口隔膜切除术 (TS) 是一种受欢迎的方法,而透口内镜肌肉切除术 (POEM) 正成为一种最少的侵入性选择.
- 本研究将Z-POEM和TS与一线ZD治疗进行比较.
研究的目的:
- 为了评估Z-POEM与Zenker Diverticulum的接器,引辅助TS的有效性.
- 在一个案例匹配研究中,比较Z-POEM和TS之间的结果和并发症.
主要方法:
- 一项与案例匹配的比较研究招募了在2015-2022年期间接受Z-POEM或TS的先天患者.
- 患者因隔膜长度,症状持续时间,年龄和性别而被一对一匹配.
- 术前和术后的吞,内镜和症状问卷被用于评估.
主要成果:
- 在每个组 (Z-POEM和TS) 中,有26名患者被匹配.
- 这两种手术的成功率都很高 (96.2%),没有死亡率.
- TS的手术时间较短,手术内并发症较少 (粘膜撕裂与泄漏).
结论:
- Z-POEM 和 TS 都是对原始Zenker Diverticulum的有效的最小侵入性治疗方法.
- 横腔隔膜切除表明手术后并发症的发生率较低,手术时间较短.
- 这项研究提供了Z-POEM和TS之间的第一次直接比较,用于Zenker Diverticulum.
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