遗传倾向和增加的环境过敏原暴露在猫过敏:大流行是一个非常好的例子
相关实验视频
Updated: May 12, 2025

08:05
Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
40.0K
Bahar Arslan1,2, Gülden Paçacı Çetin1,3, İnsu Yilmaz1
1Erciyes University School of Medicine, Department of Chest Diseases, Division of Immunology and Allergy, Kayseri, Turkey.
Allergologia et immunopathologia
|May 9, 2025
概括
随着COVID-19大流行,猫的拥有和室内时间增加,导致猫过敏的显著增加. 其他室内和花粉过敏原的敏感性没有增加,除了Penicillium过敏性降低.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 流行病学 流行病学
- 环境健康 环境健康
背景情况:
- 家庭猫是室内过敏原的主要来源.
- 随着COVID-19的流行,室内时间和过敏原的暴露增加了,特别是对猫和灰尘虫的暴露.
- 了解过敏原敏感化模式对于公共卫生至关重要.
研究的目的:
- 为了调查COVID-19流行后猫敏感化和所有权的频率.
- 分析猫类过敏和其他室内/花粉过敏原敏感化之间的关系.
- 评估在疫情封锁期间和之后对过敏原暴露的变化.
主要方法:
- 对2018-2022年被诊断为猫过敏的患者数据的回顾性分析.
- 纳入标准:对猫的过敏反应,皮肤测试呈阳性或特定免疫球蛋白E (sIgE) 水平.
- 使用皮肤刺伤测试和Phadia CAP系统FEIA进行的过敏原测试用于sIgE.
主要成果:
- 在COVID-19大流行期间,猫的拥有量显著增加 (P < 0.001).
- 猫过敏的患病率从COVID前的4.53%上升到2020年及以后的5.89% (P<0.001).
- 同时使用的Dermatophagoides farinae,Dermatophagoides pteronyssinus和花粉过敏症没有显著变化;Penicillium过敏症下降.
结论:
- 在疫情期间,猫拥有的增加和室内时间可能导致了猫过敏的增加.
- 除了猫过敏之外,其他室内过敏原 (除了Penicillium) 的敏感性没有显著增加.
- 流行病相关的生活方式变化影响了室内过敏原敏感化模式.
相关概念视频
Allergic Reactions
27.2K
Overview
27.2K
Asthma: Pathogenesis and Management
234
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
234
Asthma-I: Introduction
2.6K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
2.6K
Asthma-II: Pathophysiology and Classification
2.6K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.6K
Autoimmune Disorders
320
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
320
Background and Environment Affect Phenotype
6.4K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.4K

