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在早产营养研究中报告的营养摄入量和生长量:一个范围审查
Meiliana Meiliana1, Frank H Bloomfield1, Jane E Harding1
1Liggins Institute, University of Auckland, Auckland, New Zealand.
早产婴儿营养研究缺乏对营养摄入量和生长结果的标准化报告. 这种不一致性阻碍了基于证据的指导方针,并强调了需要最低报告要求的必要性.
科学领域:
- 新生儿科学 新生儿科学
- 营养科学 营养科学
- 临床研究方法论 临床研究方法论
背景情况:
- 对于早产婴儿的营养需求存在不一致的指导方针.
- 不确定性源于营养研究中报告的各种结果.
- 对于早产营养,需要一个标准化的报告框架.
研究的目的:
- 在早产营养研究中识别和分类营养摄入量和生长结果的措施.
- 支持制定早产营养研究的最低报告套件.
- 评估最近文献中结果报告的一致性和完整性.
主要方法:
- 进行了2018-2023年出版物的范围审查.
- 包括评估早产婴儿营养摄入量和生长的研究.
- 一位审查员选并提取数据,第二位审查员解决不确定性.
主要成果:
- 包括250项研究,报告营养摄入量计算有显著差异 (4%).
- 用多种方法报告体重 (5) 和体重增加 (13).
- 在26%的相关研究中,发现体重增加计算方法的报告不完整.
结论:
- 预产期营养研究显示出大量的异质性和关键结果的不完整报告.
- 缺乏标准化限制了当前证据的可比性和有用性.
- 标准化的报告框架对于推进早产营养研究和临床指南至关重要.
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