在2023年高度接种疫苗的澳大利亚人口中,长期Covid症状集群,相关性和预测因素
Essa Tawfiq1, Rosalie Chen1, Damian Alexander Honeyman1
1Biosecurity Program, The Kirby Institute, Faculty of Medicine and Health, The University of New South Wales, Sydney, Australia.
概括
几乎五分之一的人经历了长时间的COVID感染后,在各个年龄组和变种中存在类似的风险. 识别症状集群有助于长期COVID患者的风险评估和管理.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 传染性疾病 传染性疾病
背景情况:
- 关于在高度接种疫苗的人群中感染Omicron后长期Covid的负担的数据有限.
- 了解长期的Covid流行和预测因素至关重要,特别是在Omicron占主导地位的时期.
研究的目的:
- 在奥米克朗时代,在高度接种疫苗的澳大利亚人口中描述长期的Covid流行和预测因素.
- 在长期的Covid患者中识别关键的症状集群及其相关物.
主要方法:
- 在2023年1月,在澳大利亚进行了一项匿名,在线,横截面的调查.
- 参与者包括18岁以上的居民,有COVID-19检测阳性病史.
- 多变量后勤回归评估了长期Covid发生和严重程度的预测因素,以症状为基础的集群识别患者子组.
主要成果:
- 19.9%的参与者报告了长期的Covid.
- 风险因素包括女性性别,并发症和使用类固醇吸入器;风险随着急性感染的严重程度而增加.
- 在Omicron和pre-Omicron期间之间,或根据疫苗接种状态或年龄,在长期Covid可能性上没有显著差异.
- 确定了两个群体:无症状和多症状,后者与更糟糕的功能结果有关.
结论:
- 长期的Covid代表了澳大利亚的重大健康负担,即使是在Omicron时代.
- 识别风险因素和症状集群可以为保护弱势群体和管理长期Covid的政策提供信息.
- 累积症状计数可能有助于对长期Covid患者进行分组.
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