在迷幻研究中,不良事件不应该令人惊
Rebecca Ehrenkranz1, Manish Agrawal2, Sandeep M Nayak1
1Center for Psychedelic and Conciousness Research, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Psychedelic medicine (New Rochelle, N.Y.)
|May 9, 2025
概括
迷幻疗法提供了好处,但也带有风险. 基于临床证据的平衡观点对于公众和科学家对迷幻治疗的理解至关重要.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 迷幻药对心理健康状况具有治疗潜力.
- 当前的公共话语往往强调利益超过风险.
- 需要对迷幻药的风险和益处有一个平衡的观点.
研究的目的:
- 倡导关于迷幻疗法的更平衡的科学和公共话语.
- 突出承认风险和收益的必要性.
- 强调关于迷幻治疗的基于证据的沟通.
主要方法:
- 审查现有关于迷幻风险和益处的研究.
- 在迷幻科学中对公共话语趋势的分析.
- 考虑临床试验数据和参与者报告.
主要成果:
- 迷幻药的不良反应范围从轻度到严重.
- 增加研究和放宽资格标准可能会增加不良事件发生率.
- 量化和沟通风险/收益概况至关重要.
结论:
- 对迷幻药的风险和益处给予平衡的关注对于科学界和公众来说至关重要.
- 有必要对公众进行心理风险的性质和存在的教育.
- 关于迷幻药的风险/益处概况的有效沟通越来越重要.
更多相关视频
07:30HSV-Mediated Transgene Expression of Chimeric Constructs to Study Behavioral Function of GPCR Heteromers in Mice
Published on: July 9, 2016
7.2K
12:00Investigating the Effects of Antipsychotics and Schizotypy on the N400 Using Event-Related Potentials and Semantic Categorization
Published on: November 19, 2014
12.8K
相关概念视频
Hallucinogens and Psychedelics
145
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
145
CNS Stimulants: Psychedelic Agents
104
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
104
Altered States of Awareness
117
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
117
Ethics in Research
22.8K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
22.8K
Naturalistic Observations
15.3K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
15.3K
Blind Procedures
10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K
