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在COVID-19大流行期间,高分辨率计算机断层扫描诱导的乳腺癌的终身可归因风险

Roya Sahebi¹, Jafar Hassanzadeh², Rezvan Ravanfar Haghighi³

¹Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.

Journal of family & reproductive health

|May 9, 2025

概括

这项研究估计了乳腺癌的终身可归因风险 (LAR) 由于在伊朗什拉兹的COVID-19大流行期间使用的高分辨率计算机断层扫描 (HRCT) 扫描. 结果表明乳腺癌风险可能增加,建议谨慎使用HRCT.

科学领域:

放射学和成像学放射学和成像学
在瘤学瘤学.
公共卫生公共卫生

背景情况:

由于COVID-19大流行,人们越来越多地使用高分辨率计算机断层扫描 (HRCT) 来诊断和管理疾病.
人们对这种增加的辐射暴露对未来乳腺癌发病率的潜在长期影响感到担忧.

研究的目的:

为了估计与HRCT利用相关的乳腺癌的生命归因风险 (LAR) 在伊朗雪拉兹的COVID-19大流行期间.
提供可以为辐射安全协议和临床决策提供信息的数据.

主要方法:

在2020年2月至2022年12月期间,在希拉兹的纳马齐医院进行了一项横截面研究.
器官剂量使用CT扫描仪成像性能评估 (ImPACT) 患者剂量计计算器进行计算.
使用电离辐射生物效应委员会 (BEIR) 模型计算了生命归因风险 (LAR).

主要成果:

这项研究包括666名年龄在15-95岁之间的参与者.
25%的参与者接受了HRCT超过一次 (2-8次).
平均乳腺癌总LAR估计为每10万人中有217人 (95%不确定性极限:194-244),考虑单次和多次暴露.

结论:

这些发现突显出HRCT后辐射诱导乳腺癌的风险不可忽视.
建议包括优先考虑HRCT的超低剂量协议而不是低剂量协议.
建议临床医生避免在短时间内不必要和重复的胸部HRCT请求,以尽量减少累积的辐射暴露.

关键词:

乳腺癌乳腺癌乳腺癌在 COVID-19 疫情中,图像扫描 CT 扫描扫描扫描高分辨率计算机断层扫描 (HRCT)终身可归因的风险终身可归因的风险

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