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Updated: Jun 15, 2025

Macrophage Differentiation and Polarization into an M2-Like Phenotype using a Human Monocyte-Like THP-1 Leukemia Cell Line
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细胞外PKM2通过调节巨细胞极性来调节癌症免疫力

Guangda Peng1, Bin Li1, Hongwei Han1

  • 1Department of Biology, Georgia State University, University Plaza, Atlanta, GA, 30303, USA.

Cancer immunology, immunotherapy : CII
|May 9, 2025
PubMed
概括

细胞外PKM2通过与整合素αvβ3.3相互作用,促进瘤中M2巨的两极分化. 针对这种相互作用与抗 PKM2 抗体将 M2 转化为 M1 巨细胞,增强癌症治疗.

关键词:
阿尔金纳1 酶1癌症免疫疗法癌症免疫疗法葡萄糖溶解是什么? 葡萄糖溶解整体素 αvβ3 的组成部分.巨细胞是一个巨细胞.酸盐激酶M2的使用方法

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