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Keiko Wada¹, Wataru Suda², Tomomi Ueno³

¹Department of Epidemiology and Preventive Medicine, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu City, Gifu, 501-1194, Japan. wada.keiko.z3@f.gifu-u.ac.jp.

European journal of nutrition

|May 9, 2025

概括

儿童的Equol生产与多样化的肠道微生物群密切相关. 更丰富,更多样化的肠道微生物组组成与从大豆异黄中产生equol的能力更高有关.

科学领域:

微生物组研究的研究.
人的肠道微生物群.
代谢学代谢学代谢学

背景情况:

人体肠道微生物群与equol生产之间的关系尚未得到充分理解.
埃科尔是从大豆异黄中提取的代谢物,具有潜在的健康益处.
了解这种关系可以为饮食和健康策略提供信息.

研究的目的:

调查肠道微生物群组成与学龄儿童的生殖能力之间的关联.
为了检查性别,年龄和大豆异黄暴露对这种关系的影响.

主要方法:

1110名学龄儿童参加,累计参与率为85.2%.
在补充大豆奶后,通过尿液中的equol/daidzein比率来评估equol的产量.
在便样本上使用16S rRNA基因测序分析了肠道微生物群.

主要成果:

与非生产者相比,Equol生产者表现出明显更高的肠道微生物丰富性和多样性 (OTU数,Chao 1,Shannon指数).
肠道微生物群结构在生产者和非生产者之间有显著差异.
特定的细菌物种,包括Asaccharobacter celatus和Slackia isoflavoniconvertens,与equol生产有积极的联系.

结论:

儿童的Equol生产能力与肠道微生物群多样性有很强的相关性.
一个丰富多样的肠道微生物群,以及微生物的相互关系,似乎对于有效的equol生产至关重要.

关键词:

孩子孩子孩子孩子流行病学流行病学在Equol中使用Equol.食物频率调查问卷食物频率问卷我们的肠道微生物群.这种类型的异黄是Isoflavone.

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