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Updated: May 12, 2025

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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在生成药物设计中整合药理动力学和定量系统药理学方法

Helle W van den Maagdenberg1, Jikke de Mol van Otterloo1, J G Coen van Hasselt1

  • 1Leiden Academic Centre of Drug Research, Leiden University, 2333, Leiden, The Netherlands.

Journal of chemical information and modeling
|May 9, 2025
PubMed
概括

这项研究将药理动力学 (PK) 预测整合到生成性药物设计中,以优化癌症免疫治疗的候选药物. 通过将PK/PD建模与AI相结合,研究人员可以设计具有更高效率和向性质的分子.

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