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Updated: May 12, 2025

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将SARS-CoV-2核囊蛋白转移到未感染的上皮细胞中会诱导抗体介导的补体沉积

Jamal Fahoum1, Maria Billan2, Julia K Varga3

  • 1Department of Biochemistry, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem, Israel; Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, The Hebrew University-Hadassah Medical School, The Hebrew University of Jerusalem, Jerusalem, Israel.

Cell reports
|May 9, 2025
PubMed
概括

细胞表面上的细胞外SARS-CoV-2核蛋白 (NP) 触发了对COVID-19患者的破坏性抗体和补充反应. 埃诺沙巴林可以通过阻断NP结合来预防这种病理.

关键词:
C3b补充沉积沉积 C3b补充沉积COVID-19 的严重程度.CP: 免疫学 免疫学这是SARS-CoV-2抗体.在SARS-Cov-2核囊蛋白质中.经典补充路径的经典补充路径静电相互作用 静电相互作用埃诺克萨帕林 (Enoxaparin) 是一种灵活的链接器 灵活的链接器肝硫酸盐蛋白质甘油 蛋白质甘油 肝硫酸盐蛋白质甘油硫酸葡萄糖氨基酸葡萄糖甘油

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