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Utilizing Transcranial Magnetic Stimulation to Study the Human Neuromuscular System
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一个用于高频跨脊柱磁刺激 (HF-TSMS) 的准共振系统.

Francesca Marturano, Don Straney, Micol Colella

    IEEE transactions on bio-medical engineering
    |May 9, 2025
    PubMed
    概括

    一个新的高频跨脊柱磁刺激 (HF-TSMS) 系统提供了一个非侵入性的,具有成本效益的解决方案. 这项创新技术展示了在临床环境中安全有效的慢性疼痛管理的潜力.

    科学领域:

    • 生物医学工程 生物医学工程
    • 神经科学是一个神经科学.
    • 医疗器械 医疗器械

    背景情况:

    • 非侵入性神经调节技术对于治疗应用至关重要.
    • 现有的磁刺激方法往往面临效率和成本的局限性.
    • 高频跨脊柱磁性刺激 (HF-TSMS) 是脊髓干预的有希望的途径.

    研究的目的:

    • 设计,开发和验证一种新的非侵入性HF-TSMS系统.
    • 为了实现脊髓纤维的高效和选择性刺激.
    • 探索HF-TSMS在临床应用中的潜力,特别是在疼痛管理方面.

    主要方法:

    • 开发具有可定制参数的准共振脉冲宽度调制 (PWM) 系统.
    • 使用一个定制的Figure-8线圈,优化了脊髓纤维的准.
    • 实施顺序控制的零电流切换 (SCZCS) 以尽量减少能量损失.

    主要成果:

    • 该系统通过准共振成功产生了高电流 (10 kA) 脉冲,使用明显较低的输入电压.
    • 初步的动物研究证实,产生的脉冲有效地到达了脊髓.
    • 在实验期间,HF-TSMS系统证明了安全运行,没有显著的线圈加热.

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    结论:

    • 开发的HF-TSMS系统提供了一种高效,具有成本效益和低损失的方法来产生高频电流脉冲.
    • 这项技术具有很大的潜力,可以被纳入临床实践,作为一种安全的,非侵入性的慢性疼痛治疗方法.