在高血压疾病中,第二到第四位数比率 (2D:4D)
Refik Servi1, Ramazan Fazil Akkoc1, Feyza Aksu1
1Department of Anatomy, Faculty of Medicine, Firat University, Elazig, Turkey.
概括
第二到第四位数的比率 (2D:4D) 可以预测高血压风险. 与对照组相比,患有高血压的个体在两只手中的2D:4D比率显著更高,这表明其作为早期风险指标的潜力.
科学领域:
- 内分泌学 在内分泌学.
- 心血管医学 心血管医学
- 人类测量学 人类测量学.
背景情况:
- 第二到第四位数的比率 (2D:4D) 是一种性二态特征,受到产前性激素暴露的影响.
- 该比率已被研究为各种成人疾病的潜在生物标志物,包括心血管疾病.
- 以前的研究表明,2D:4D与心血管疾病风险之间存在联系.
研究的目的:
- 为了研究诊断为高血压的患者双手中的2D:4D比率.
- 为了比较高血压患者和健康对照组之间的2D:4D比率.
- 为了确定2D:4D是否在高血压和非高血压受试者之间有显著差异.
主要方法:
- 该研究包括400名高血压患者 (200名男性,200名女性) 和400名健康对照.
- 2D:4D比率是通过测量所有参与者的双手第二和第四个手指的长度来计算的.
- 两组的身高,体重和体重指数 (BMI) 也被记录下来.
主要成果:
- 与正常体重控制组相比,高血压患者的平均BMI显著更高,属于超重类别 (p < 0.001).
- 与对照人群相比,高血压男性和女性的2D:4D比率显著更高.
- 这种高的2D:4D比在高血压组的右手和左手之间是一致的 (p = 0.001对于男性,p < 0.001对于女性).
结论:
- 2D:4D比率可以作为个体从出生就有高血压倾向的重要指标.
- 被确定具有较高的2D:4D比率的个体可能被认为具有更高的风险,从而使主动的生活方式选择.
- 这一发现突显了2D:4D作为高血压风险评估的非侵入性生物标志物的潜力.
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