毛细血管补充用于评估败血症中的循环功能障碍:一个范围审查
Robert L Cloutier1, Jessica Bailey1, Matthew Hansen1
1Department of Emergency Medicine Oregon Health and Science University, Portland, OR, United States of America.
The American journal of emergency medicine
|May 9, 2025
概括
毛细血管补充时间 (CRT) 在评估与败血症相关的循环功能障碍方面表现有前途. 然而,需要进一步的研究来提高测量可重现性,并验证其在试验中的临床实用性.
科学领域:
- 关键护理医学 关键护理医学
- 紧急医疗 紧急医疗
- 临床生理学 临床生理学
背景情况:
- 败血症诊断在美国急诊室 (ED) 和重症监护室 (ICU) 中具有挑战性.
- 循环功能障碍是败血症严重程度的关键指标.
研究的目的:
- 对有关毛细血管补充时间 (CRT) 的文献进行范围审查,以评估败血症中的循环功能障碍.
- 了解当前的证据基础,并识别研究缺口.
主要方法:
- 遵守PRISMA指导方针进行范围审查.
- 在OVID Medline (1946-2022) 中进行系统的文献搜索,确定了800篇文章,其中13篇被列入最终分析.
- 包括在ED和ICU设置中测量CRT的研究,评估指甲床颜色回归时间;使用纽卡斯尔-太华评分评估的研究.
主要成果:
- 在包括的13项研究中,证据的强度中等.
- 在CRT测量技术中发现了方法上的缺陷和变化.
- 在不同研究中测量了毛细血管补充的不一致的可重现性.
结论:
- 毛细血管补充时间有可能作为败血症评估中的辅助.
- 需要新兴技术来提高床边测量的可复制性和可靠性.
- 需要前性随机对照试验来验证CRT对患者结果的预测价值.
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