COVID-19死亡风险的演变:印度法里达巴德的三次流行浪潮的回顾性研究
L Parashar1, G G Meshram2, S L Vig3
1Department of Statistics, Amity School of Applied Sciences, Amity University, Jaipur 303002, Rajasthan, India.
Semergen
|May 9, 2025
概括
在印度的流行病浪潮中,COVID-19死亡风险因素发生了转变. 伴随性疾病和严重疾病仍然是关键因素,而社会人口统计学影响随着时间的推移而减少,特别是在峰值浪潮期间.
科学领域:
- 流行病学 流行病学
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
背景情况:
- 2019年新冠病毒病 (COVID-19) 在全球范围内呈现出明显的流行病浪潮.
- 了解COVID-19死亡率的不断变化的风险因素对于公共卫生战略至关重要.
研究的目的:
- 为了比较印度法里达巴德的三个不同的流行病浪潮中与COVID-19死亡率相关的社会人口统计学,并发病率和临床变量.
主要方法:
- 从印度法里达巴德的第三级护理中心回顾分析了5217名COVID-19患者的病历.
- 流行病浪潮的分类:第一波 (2020年4月至2021年1月),第二波 (2021年3月至2021年6月),第三波 (2021年12月至2022年2月).
- 使用奇平方和科克兰-阿米塔奇测试进行统计分析,以评估与死亡率的关联以及跨波的趋势.
主要成果:
- 伴随性疾病 (糖尿病,高血压),多病症和需要ICU/呼吸机支持的严重疾病始终与更高的COVID-19死亡率有关.
- 社会人口统计学因素在前两波死亡率上产生了重大影响,但在第三波死亡率下降.
- 像"感冒和流感"这样的临床症状在所有波中仍然显著;死亡率在第二波中达到顶峰,不成比例地影响女性,老年人,以及患有并发症或严重症状的人.
结论:
- 转移COVID-19死亡风险因素需要适应性的公共卫生干预措施.
- 在流行病浪潮高峰期优先考虑高风险群体对于优化资源配置和降低死亡率至关重要.
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