患者报告的食品免疫治疗结果在国家和食物之间有所不同:来自COFAITH的结果
Pablo Rodríguez Del Río1, Carmen Riggioni2, Antoine Deschildre3
1Allergy Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain; FibHNJ, RICORS center RD24/0007/0037 Instituto de Salud Carlos III, Madrid, Spain; IIS La Princesa, Madrid, Spain.
概括
患者对食物过敏原免疫治疗 (FAIT) 的看法揭示了不同的愿望和动机. 了解这些患者报告的结果是改善FAIT治疗的感知价值的关键.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 临床研究 临床研究
- 患者报告的结果
背景情况:
- 食物过敏原免疫疗法 (FAIT) 是指导方针推的治疗方法,基于研究人员定义的指标,其有效性已被证明.
- 然而,有限的研究已经探索了患者的观点和患者报告结果 (PRO) 在FAIT中的相关性.
研究的目的:
- 在食物过敏原免疫疗法 (FAIT) 的背景下,研究和理解各种患者报告结果 (PRO) 的意义.
主要方法:
- 欧洲过敏和临床免疫学会 (EAACI) 工作组开发了一个问卷,从儿童FAIT患者的护理人员那里收集数据.
- 收集了有关社会经济因素,过敏史,FAIT方法,负担,安全和食物过敏生活质量 (FAQoL) 的信息.
- 根据相关性排列了19个拟议的PRO,并对收集的数据进行了描述性和集群分析.
主要成果:
- 这项研究包括857名从欧洲和北美招募的接受牛奶,花生或蛋FAIT的患者.
- 食物过敏生活质量 (FAQoL) 评分因地区和FAIT类型而异,南欧人报告得分更高,牛奶/蛋FAIT与花生FAIT相比得分更差.
- 集群分析根据他们的PRO反应确定了五种不同的患者表型:"高期望"",超越保护"",社会功能"",旨在正常化"和"低动机".
结论:
- 这种数据驱动的分析突出了FAIT.患者愿望的复杂性和个性化.
- 这些发现为未来的研究开辟了道路,旨在提高患者对食物过敏原免疫疗法的感知价值.
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