年龄和性别平等是否会影响孕妇和产后母的氧化特征?
R R Rosa Filho1, D S França1, M A Alonso1
1Department of Animal Reproduction, School of Veterinary Medicine and Animal Science, University of São Paulo, Av Orlando Marques de Paiva, 87, São Paulo, SP, Brazil, 05508-270.
Journal of equine veterinary science
|May 9, 2025
概括
孕妇的年龄会影响孕妇在怀孕晚期和产后的抗氧化剂水平. 年龄较大的母马显示高谷过氧化酶,表明年龄影响了马类繁殖中的氧化应激管理.
科学领域:
- 生殖生理学 生殖生理学
- 氧化应激研究研究 氧化应激研究
- 马类内部医学 马类内部医学
背景情况:
- 孕期增加了能量和氧气需求,导致反应性氧物种的产量增加.
- 母亲年龄和对氧化应激的平价效应在人类身上得到了记录,但在马身上不那么明显.
研究的目的:
- 为了研究在孕期晚期和产后期间马匹的氧化变化.
- 评估母体年龄和母体平价对马氧化特征的影响.
主要方法:
- 根据年龄 (3-7,8-11,≥12岁) 和平价 (无双,1-3,4-6岁) 分组了17只母马.
- 评估的氧化应激标志物:铁酸反应物质 (TBARS),蛋白质氧化,总铁和.
- 测量了抗氧化酶的活性:谷氨过氧化酶,谷氨减氧化酶和超氧化物脱化酶.
主要成果:
- 年龄和妊娠时间之间的相互作用影响了水平.
- 较老的母马表现出更高的谷氨过氧化酶活性,观察到时间效应.
- 没有发现谷氨减少酶,超氧化物转化酶,脂质/蛋白质氧化或总铁的显著变化.
结论:
- 孕产妇的年龄在妊娠晚期,分娩和产后期间显著影响马匹的谷氨过氧化酶和的度.
- 这项研究提供了对母体年龄相关的氧化变异和马的抗氧化机制的见解.
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