社会经济和人口变量在阴道切除术中缺乏随机对照试验:系统性审查
Mark Kurapatti1, Laurel Wong1, Ha-Neul Yu2
1Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY.
概括
阴道切除术随机对照试验 (RCT) 往往没有报告年龄和性别以外的关键社会人口统计因素. 未来的骨科研究必须包括这些变量,以提高概括性和临床相关性.
科学领域:
- 整形外科手术 整形外科手术
- 临床试验方法论 临床试验方法论
- 医疗保健服务研究 医疗服务研究
背景情况:
- 社会人口统计学因素显著影响健康结果和治疗反应.
- 了解临床试验中的患者人群对于概括性至关重要.
- 阴道切除术是一种常见的骨科手术,但试验报告可能不完整.
研究的目的:
- 评估社会人口学变量在随机对照试验 (RCT) 中的纳入,重点关注阴道切除术结果.
- 评估当前脑膜切除RCT在多大程度上考虑了患者的不同特征.
主要方法:
- 搜索了PubMed,Embase和MEDLINE在2014年至2024年之间发表的男性切除术RCT.
- 评估了11个独特的RCT,用于报告13个特定的社会人口统计变量.
- 通过使用费舍尔精确测试分析报告中的时间趋势.
主要成果:
- 所有11个包括的RCT报告了年龄;90.9%报告了性别和体重指数 (BMI).
- 报告其他变量,如种族/种族,就业状况和语言能力特别低 (9.1%至36.4%).
- 任何研究都没有报告社会经济地位,保险和婚姻状况等关键因素.
结论:
- 高影响力脑膜切除术RCT显示,关键社会人口统计学变量报告不足.
- 连续纳入这些变量对于提高脑膜切除研究的外部有效性和临床实用性至关重要.
- 未来的骨科研究应该优先考虑对社会人口统计数据的全面报告,以提高概括性和可复制性.
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