喉参与复发性多合体炎:173名患者的临床和CT发现
Xiao Bai1, Ruohan Yu2, Zhengang Wang3
1Department of Rheumatology and Immunology, Beijing Tsinghua Changgung Hospital, Beijing, China.
复发性多重合体炎 (RP) 经常导致呼吸道损伤,特别是在喉,即使在无症状患者中. 典型的CT检测结果,比如状体侵蚀,需要对早期检测和管理进行警监测.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 放射学 放射学是一门学科.
背景情况:
- 复发性多合体炎 (RP) 是一种罕见的自身免疫性疾病,向软骨.
- 喉参与RP可能会导致严重的气道损害.
研究的目的:
- 描述临床特征和CT发现的喉参与RP.
- 为了确定CT模式与喉RP的临床表现相关.
主要方法:
- 对173名确诊的RP患者进行了回顾性分析.
- 对喉,气管和支气管CT扫描进行审查.
- 统计分析与喉干扰和狭窄相关的因素.
主要成果:
- 41.1%的患者表现出喉干扰;66%的无症状患者在CT上有呼吸道损伤.
- 主要的喉发现包括状体侵蚀和扩大与粘膜增生.
- 发病时年龄较小,疾病持续时间较长,多器官参与与喉疾病有关.
结论:
- 在RP呼吸道疾病中,喉干扰是常见的,特定的CT发现是特征性的.
- 早期检测和管理对于具有风险因素的RP患者至关重要.
- 对高风险RP子组的有针对性的干预措施需要进一步的研究.
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