在婴儿时接种疫苗的医疗实习生中,抗HBs持久性和历史回应
Nesrine Fathi Hanafi1, Nashwa Naguib Omar2, Ghada Abdelwahed Ismail2
1Department of Medical Microbiology and Immunology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
许多医疗实习生尽管接种婴儿疫苗,但缺乏保护性乙型肝炎免疫力. 增强剂恢复了所有参与者的免疫力,强调了预防乙型肝炎病毒感染的查和增强剂的必要性.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 医疗实习生面临着感染乙型肝炎病毒 (HBV) 的高风险.
- 疫苗接种对于减少全球HBV发病率至关重要.
- 疫苗诱导的对HBV的长寿保护仍在争论中.
研究的目的:
- 为了确定在婴儿时接种疫苗的医疗实习生中的抗HBs抗体水平.
- 评估那些没有保护标位的人对HBV疫苗增剂剂的免疫反应.
主要方法:
- 一项涉及519名2022年医疗实习生的横截面研究.
- 免疫记录和血液样本检测HBsAg和抗HBs的分析.
- 对抗HBs<10mIU/mL的参与者给予HBV强剂,然后再进行测试.
主要成果:
- 58.6%的实习生具有保护性抗HBs标位 (≥10mIU/mL).
- 41.4%的实习生表现出非保护性的抗HBs标位 (<10 mIU/mL).
- 所有接受强剂的实习生在2个月内实现了保护标位.
结论:
- 很大一部分医疗实习生缺乏足够的HBV保护.
- 对抗HBs水平的查和提供强剂量是必不可少的.
- 需要采取积极的措施来保护卫生保健工作者免受HBV感染.
更多相关视频
08:04Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
Published on: July 9, 2014
15:57Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
相关概念视频
Immunological Memory
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
Vaccinations
Development of Immunocompetence
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Cells of the Adaptive Immune Response
Active versus Passive Immunity
Active Immunity
Active immunity refers to the resistance one develops...
Cross-reactivity
