用假牙修复缺失的牙与认知功能之间的关联
Lata Goyal1, Komal Kaur Saroya2, Shipra Gupta3
1Periodontology Division, Department of Dentistry, All India Institute of Medical Sciences, Bathinda, India. latagoyal83@gmail.com.
Evidence-based dentistry
|May 9, 2025
概括
戴假牙可能会降低牙损失患者认知障碍的风险. 这一系统性审查和元分析表明,及时修复假牙可以防止认知能力下降.
科学领域:
- 老年学是一门学科.
- 牙科科学 牙科科学
- 神经科学是一个神经科学.
背景情况:
- 牙脱落是一个普遍的问题,特别是在老年人中.
- 认知障碍,包括痴呆症,构成了重大的公共卫生挑战.
- 口腔健康,特别是牙损失及其恢复与认知功能之间的关系仍然是积极研究的领域.
研究的目的:
- 系统地审查和分析调查假牙修复与牙损失和认知障碍之间的关联的观察性研究.
- 量化牙损失个体的认知障碍风险,比较那些做和不接受假牙修复的人.
主要方法:
- 从2000年1月到2024年1月,对五个电子数据库 (PubMed,EMBASE,Cochrane Library,MEDLINE,CNKI) 进行了全面的搜索.
- 在分析中包括了6项观察性研究,共有24,252名参与者.
- 使用随机效应模型计算出具有95%置信区间 (CI) 的风险比率 (RR),并进行质量评估和出版偏差分析.
主要成果:
- 没有戴假牙的失去牙的个体与戴假牙的人相比,认知障碍的几率高出1.27倍 (1.02倍).
- 在没有假牙的组中,每颗额外缺失的牙增加了认知障碍的风险1.009倍,而在假牙组中是1.003倍.
- 在非假牙组中,出版偏差是显著的,但在假牙修复组中没有.
结论:
- 牙修复似乎与牙损失的个体认知障碍的风险降低有关.
- 这些发现表明,及时修复假牙可能在缓解认知衰退方面发挥保护作用.
- 需要进一步的纵向和干预研究来确定因果关系.
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