长期的手术后缺甲状腺症的失律负担通过24小时的霍尔特心电图进行评估
Rachele Santori1, Vito Menafra1, Alessandro Sgreccia1
1Department of clinical, internal, anesthesiology and cardiovascular sciences, "Sapienza" University of Rome, Rome, Italy.
Endocrine
|May 9, 2025
概括
经过长期术后偏偏甲状腺症的绝经后妇女经历了心律失常和心脏功能减弱的增加,即使没有心脏结构问题. 这项研究强调了这个患者群体中早发性心跳和较低射出率的风险更高.
科学领域:
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
背景情况:
- 术后偏偏甲状腺症与心血管风险有关,但其对心律失常的影响仍有争议.
- 了解长期缺甲状腺症对心脏的影响对于患者管理至关重要.
研究的目的:
- 为了研究经更年期妇女的心律失常风险和心脏功能,这些妇女患有长期的术后性甲状腺功能低下症.
- 为了比较下巴甲状腺患者和健康对照者之间的心脏参数.
主要方法:
- 一项病例对照研究,涉及22名经更年期后患有术后偏甲状腺症的女性和22名健康对照人.
- 评估包括血液测试,12导电图,12小时霍尔特监测和心声回声.
- 排除标准确保专注于缺甲状腺症的影响,不包括先前存在的心血管疾病或相关药物.
主要成果:
- 与对照组相比,甲状腺功能低下患者的血清和PTH水平显著降低,水平更高.
- 超心室和心室过早跳动的发病率在甲状腺下垂体组中较高.
- 降低心率变化 (横交感活动) 和较低的射出分数在低甲状腺患者中被观察到.
- 低甲状腺症持续时间较长与心率增加,QRS持续时间和射出分数减少相关.
结论:
- 24小时的霍尔特监测显示,更年期后妇女患有长期术后偏甲状腺功能障碍症时,心律失常的患病率增加.
- 这些心律失常风险和功能变化发生,尽管没有延长的QT间隔或结构性心脏异常.
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