为年轻成年人提供HIV暴露前预防的全国趋势,2016-2023年
Nina E Hill1,2,3, Sijia He4, Kao-Ping Chua4
1Susan B Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA. ninahill@med.umich.edu.
Journal of general internal medicine
|May 9, 2025
概括
从2016年到2023年,向年轻人发放艾滋病毒暴露前预防药物 (PrEP) 的数量显著增加,但治疗时间缩短. 需要继续努力,以改善PrEP的坚持和保持在这个人口群的护理.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 预防艾滋病毒 预防艾滋病毒
背景情况:
- 美国年轻人占艾滋病毒新诊断的很大一部分.
- 没有先前的国家研究分析了HIV暴露前预防药物 (PrEP) 为这一年龄组发行的最新趋势.
研究的目的:
- 评估2016年至2023年美国年轻成年人PrEP发行趋势.
主要方法:
- 使用IQVIA纵向处方数据库进行的横截面研究.
- 分析了年龄在18-25岁的年轻成年人中季度PrEP发行率,启动率和平均持续率.
- 加入点回归分析以确定趋势变化和按年龄分类的子组分析.
主要成果:
- 每10万年轻成年人每季度PrEP发放率从2016年的26.4增加到2023年的208.4.
- 准备剂的启动率趋势反映了分发趋势.
- 2016年至2023年间,平均PrEP持续时间从111.6天降至98.4天,年轻人表现较低.
结论:
- 在美国的年轻人中,PrEP的发行和启动正在增加.
- 在这个人群中,PrEP治疗期间的持续时间正在减少.
- 需要改进的策略来改善患者的留守和坚持PrEP治疗.
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